关键词： COPD   COVID-19   Vaccination rate   Influencing factors   OBSTRUCTIVE PULMONARY-DISEASE   ADULTS   MANAGEMENT   HESITANCY   COVERAGE   CHINA  

摘要： In this study, we investigated the status and influencing factors of coronavirus disease 2019 (COVID-19) vaccination in patients with chronic obstructive pulmonary disease (COPD). A questionnaire on COVID-19 vaccination in patients with COPD was developed. The clinical characteristics, COVID-19 vaccination status, other relevant vaccinations, and vaccination status of the patients with COPD were collected anonymously. Logistic regression analysis was used to analyze the factors influencing COVID-19 vaccination in patients with COPD. There were 1898 returned questionnaires, of which 1874 were valid. The proportion of patients who completed the COVID-19 vaccination program was 78.60%. Factors influencing the COVID-19 vaccination rate were: the age of individuals who were 75-85 years old and > 85 years old, acute exacerbation 3-4 times in the previous year, comorbid cardiovascular and endocrine system diseases, failure to take regular medication for COPD, application of non-invasive ventilation machines, believing that their current health condition has deteriorated, believing that the current COVID-19 vaccine is not safe, medical staff not specifying whether they would recommend vaccination against COVID-19, medical staff not recommending the COVID-19 vaccine, and fear of adverse reactions and aggravation of COPD. Patients with COPD had a high COVID-19 vaccination rate in China, whereas patients with pneumonia, influenza, and herpes zoster had a low vaccination rate. Improving the patients' understanding of the safety and effectiveness of the vaccine and promoting effective communication between medical staff and patients would help increase the vaccination rate of patients with COPD.

关键词： COVID-19   Ireland   mental health   online learning   third-level students   SELF-EFFICACY   DEPRESSION  

摘要： Objective COVID-19 forced third-level students to transition to online learning (OL). Many students encountered issues with OL, such as accessibility. However, the relationship between OL issues and mental health during this time remains poorly understood. Participants: Third-level students in Ireland (N = 268) completed an online questionnaire examining experiences with OL and mental health during COVID-19. Methods: OL social, lecturer, accessibility, individual skills, and environment issues, were entered into logistic regression analyses to examine whether these variables predicted mental health outcomes and/or preference to keep OL. Results: Students reporting more individual skills issues were more likely to attain a probable diagnosis of posttraumatic stress disorder, complex posttraumatic stress disorder, and depression (p < 0.0083); students who reported more environment issues were less likely to report preference to keep OL (p < 0.0005). Conclusions: Given individual skills issues associated with worse mental health, future research should examine improving student perceptions of their own OL skills.

关键词： future time perspective   COVID-19 pandemic   young adults   university students   optimism   well-being   YOUNG-ADULTS   ADOLESCENTS   ORIENTATION   THINKING   LIFE   DEPRESSION   VALIDATION   ANXIETY   STRESS  

摘要： Introduction During the COVID-19 pandemic, young adults worldwide showed signs of distress as they were affected in their specific developmental tasks, including the construction of personal and professional *** The present study aimed to assess the situational future time perspective of Italian university students during the second pandemic wave, as measured by an ad hoc constructed instrument, to explore its interaction with some dispositional traits relevant in future construction, such as optimism, sense of life, aggression, and dispositional future time perspective, and to test their effect on psychological well-being. The total sample consisted of 389 subjects (18-35 years, M = 23.5, SD = 4.4).Results and discussion The results indicated that the pandemic experience, assessed by surveying specific indicators, negatively affected the future time perspective of students, particularly those dispositionally optimistic and convinced that life has meaning. However, awareness of the negative impact that the pandemic brought to the vision of the future seems to have dampened the levels of depression and stress, while anxiety was found to be related only to dispositional traits. The results also suggested the need for educational and economic policies that help young adults develop confidence in the future and in their ability to build it.

关键词： Physical exercise   sleep quality   weight gain   STRESS  

摘要： Introduction: Short sleep, physical inactivity, and being locked up are risk factors for weight gain. Objective: We evaluated weight gain according to sex, age, hours of sleep and physical activity in university students from 10 Latin American countries during the COVID-19 pandemic. Methods: Cross-sectional and multicenter study (n = 4880). Results: The average age was 22.5 +/- 4.4 years. 60.2% were currently locked up. 73.6% were women, 48.2% increased their body weight, 66% reported insufficient sleep hours, and 65.9% were inactive. Women gained more weight than men (73.2%) and younger students gained more weight (85.1%). Those who had insufficient sleep hours gained most weight (67.6%). Inactive participants gained most weight (74.7%). Students who have insufficient sleep are 21% more likely to have changes in body weight compared to students who have optimal sleep. Conclusion: The increase in body weight and its risk factors during confinement should be considered as emerging from public health.

关键词： virus   COVID   SARS-CoV-2   viral infection   migraine   inhibitor   GENE-RELATED PEPTIDE   PROVOCATIVE MOTION   CGRP   RESPONSES   BEHAVIOR   PROFILE  

摘要： COVID-19 can cause neurological symptoms such as fever, dizziness, and nausea. However, such neurological symptoms of SARS-CoV-2 infection have been hardly assessed in mouse models. In this study, we infected two commonly used wild-type mouse lines (C57BL/6J and 129/SvEv) and a 129S calcitonin gene-related peptide (alpha CGRP) null-line with mouse-adapted SARS-CoV-2 and demonstrated neurological signs including fever, dizziness, and nausea. We then evaluated whether a CGRP receptor antagonist, olcegepant, a "gepant" antagonist used in migraine treatment, could mitigate acute neuroinflammatory and neurological signs of SARS-COV-2 infection. First, we determined whether CGRP receptor antagonism provided protection from permanent weight loss in older (>18 m) C57BL/6J and 129/SvEv mice. We also observed acute fever, dizziness, and nausea in all older mice, regardless of treatment. In both wild-type mouse lines, CGRP antagonism reduced acute interleukin 6 (IL-6) levels with virtually no IL-6 release in mice lacking alpha CGRP. These findings suggest that migraine inhibitors such as those blocking CGRP receptor signaling protect against acute IL-6 release and subsequent inflammatory events after SARS-CoV-2 infection, which may have repercussions for related pandemic or endemic coronavirus outbreaks. IMPORTANCE Coronavirus disease (COVID-19) can cause neurological symptoms such as fever, headache, dizziness, and nausea. However, such neurological symptoms of severe acute respiratory syndrome CoV-2 (SARS-CoV-2) infection have been hardly assessed in mouse models. In this study, we first infected two commonly used wild-type mouse lines (C57BL/6J and 129S) with mouse-adapted SARS-CoV-2 and demonstrated neurological symptoms including fever and nausea. Furthermore, we showed that the migraine treatment drug olcegepant could reduce long-term weight loss and IL-6 release associated with SARS-CoV-2 infection. These findings suggest that a migraine blocker can be protective for at

关键词： Academia   COVID-19   fulfillment   higher education   mental health   ANXIETY STRESS SCALES   SELF-DETERMINATION THEORY   NORMATIVE DATA   MENTAL-HEALTH   DEPRESSION   PERSONALITY   MOTIVATION   DASS-21   VERSION   LIFE  

摘要： Objective: Researchers sought to examine experiences of stress, mental health, and work outcomes for those in higher education during the COVID-19 pandemic. Participants: Graduate students and professors completed an online survey in June 2020 (N = 1,794). Methods: Participants completed measures of stress, depression, and anxiety as well as items related to work quality, productivity, and fulfillment. Results: 70% of graduate students reported higher than normal levels of anxiety, depression, and stress according to the DASS-21. Nearly half of professors reported higher than normal levels of anxiety, depression, and stress. Multiple linear regression analyses found that higher levels of work fulfillment predicted greater productivity (f(grad)(2) = .15; f(prof)(2) = .08) and quality of work (f(grad)(2) = .10; f(prof)(2) = .12). Conclusions: Individuals in higher education are struggling with their mental health and considerations need to be made to help this group. Additionally, we discuss the implications of self-determination theory on work fulfillment.

关键词： hepatitis C virus   screening   SARS-CoV-2   COVID-19 pandemic   prison   ELIMINATION   PEOPLE  

摘要： Background Little is known about the impact of the COVID-19 pandemic on hepatitis C (HCV) screening efforts in carceral settings. We explored the impact of the pandemic on HCV screening in two of Quebec's largest provincial *** Retrospective data of HCV-related laboratory tests between July 2018 and February 2022 at l'& Eacute;tablissement de d & eacute;tention de Montr & eacute;al (EDM) and l'& Eacute;tablissement de d & eacute;tention de Rivi & egrave;re-des-Prairies (EDRDP) were obtained. To examine the association between the pandemic and the number of HCV-antibody (HCV-Ab) tests, a three-level time period variable was created: pre-outbreak, outbreak, and post-outbreak. Negative binomial regression (with monthly admissions as an offset) was used to assess the change in HCV-Ab tests across time periods and by prisons. Adjusted odds ratios (aOR) with 95% confidence intervals (95% CI) were *** A total of 1,790 HCV-Ab tests were performed; 56 (3%) were positive. Among these, 44 (79%) HCV RNA tests were performed; 23 (52%) were positive. There was a significant decrease in HCV-Ab screening at EDM during the outbreak (aOR 0.29; 95% CI 0.17-0.48) and post-outbreak (aOR 0.49; 95% CI 0.35-0.69) periods, compared to the pre-outbreak period. There was no significant change in HCV-Ab screening at EDRDP during the outbreak (aOR 0.98; 95% CI 0.49-2.11) but a significant increase in HCV-Ab screening post-outbreak (aOR 1.66; 95% CI 1.04-2.72).Conclusion The COVID-19 pandemic negatively affected HCV screening at EDM but had minimal impact at EDRDP. To eliminate HCV from carceral settings, minimizing screening interruptions during future outbreaks and combined HCV/SARS-CoV-2 screening should be prioritized.

关键词： Nomophobia   smartphone addiction   COVID-19   university students   problematic smartphone use   CULTURAL-DIFFERENCES  

摘要： Background This study aimed to: (a) explore differences in the prevalence of nomophobia and smartphone addiction (SA) from pre- to during COVID-19; (b) identify students' self-reported changes in smartphone reliance and screen time during COVID-19; and (c) examine whether self-perceived changes in smartphone usage predicted nomophobia and SA scores. Methods Scores on the Nomophobia Questionnaire and Smartphone Addiction Scale between two surveys administered at two timepoints were compared: Sample 1 (September 2019-January 2020; N = 878) and Sample 2 (May-June 2020; N = 258). Results No significant differences were found between samples on nomophobia or SA. Nearly all of Sample 2 reported using some type of app more, using their smartphone a little more, and about the same perceived smartphone reliance during COVID-19. Increased screen time, smartphone reliance, and social media significantly predicted nomophobia and SA. Conclusion COVID-19 does not appear to have exacerbated the prevalence of nomophobia or SA.

关键词： Indonesia   Stability   COVID-19   Credit relaxation   Credit restructuring   IMPACT   CRASH  

摘要： PurposeThis study aims to investigate the effect of credit relaxation policy during the COVID-19 pandemic and its efficacy as a countercyclical policy on bank risk and stability. Design/methodology/approachUsing a sample of 39 listed Indonesian banks, the authors investigate the effect of credit relaxation policy on banks' risk and stability. Data were retrieved from Eikon DataStream from monthly financial statements from June 2019 to December 2020. The authors use panel data analysis with a fixed-effect estimator to estimate the model. FindingsThe authors find that the credit relaxation policy affects banks' stability. The authors also find no significant relationship between the policy and bank risk measured by non-performing loans. The authors also find that the policy mainly affects small banks and both state-owned and private banks. Originality/valueThis research has some policy implications that issuing prompt regulations to respond to urgent situations is needed and is very important to face crisis conditions and reduce the negative impact of such crises.